Cooling and rewarming for brain ischemia or injury: Theoretical analysis

Chenguang Diao, Liang Zhu, Huan Wang

Research output: Contribution to journalArticle


A three-dimensional theoretical model was developed to examine the transient and steady state temperature distribution in the brain during selective brain cooling and rewarming. Two cooling approaches were proposed, one was packing the head with ice, and the other was wearing a cooling helmet. As such, simulation was conducted to evaluate the cooling penetration and the characteristic cooling time of both approaches.

Original languageEnglish (US)
Pages (from-to)346-353
Number of pages8
JournalAnnals of Biomedical Engineering
Issue number3
StatePublished - Jan 1 2003


  • Bioheat transfer
  • Brain ischemia
  • Head injury
  • Hypothermia
  • Multiple sclerosis
  • SBC

ASJC Scopus subject areas

  • Biomedical Engineering

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