Microspheres containing encapsulating 9-chloro-2-ethylellipticinium acetate (CME) were prepared to demonstrate that biodegradable polymers encapsulating CME are capable of intracerebral drug delivery in a controlled release manner. In vitro assays showed inhibition of cellular growth. In vivo analysis revealed no apparent toxicity from implants and all animals recovered from the implants with no signs of abnormal behavior.
|Original language||English (US)|
|Number of pages||2|
|Journal||American Chemical Society, Polymer Preprints, Division of Polymer Chemistry|
|State||Published - Aug 1 1999|
ASJC Scopus subject areas
- Polymers and Plastics