Control of patient response to anesthesia using ℒ1 adaptive methods

Evgeny Kharisov, Carolyn L. Beck, Marc Bloom

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, we discuss the use of recently developed ℒ1-adaptive control methods for closed-loop control of anesthesia delivery during surgery. Our main objectives are the design of feedback controllers ensuring that the patient's Bispectral Index profile tracks a prespecified reference trajectory whilst maintaining adherence of vital signs within safe ranges, and demonstrating robustness to interpatient variability. The controllers are designed from identification-based models constructed from clinical trial data. Simulation results are provided demonstrating the effectiveness of the control methods.

Original languageEnglish (US)
Title of host publicationProceedings of the 8th IFAC Symposium on Biological and Medical Systems, BMS 2012
PublisherIFAC Secretariat
Pages391-396
Number of pages6
Edition18
ISBN (Print)9783902823106
DOIs
StatePublished - 2012
Event8th IFAC Symposium on Biological and Medical Systems, BMS 2012 - Budapest, Hungary
Duration: Aug 29 2012Aug 31 2012

Publication series

NameIFAC Proceedings Volumes (IFAC-PapersOnline)
Number18
Volume45
ISSN (Print)1474-6670

Other

Other8th IFAC Symposium on Biological and Medical Systems, BMS 2012
CountryHungary
CityBudapest
Period8/29/128/31/12

Keywords

  • Anesthesia
  • Automatic drug delivery
  • Fast adaptation
  • Medical systems
  • Robust adaptive control

ASJC Scopus subject areas

  • Control and Systems Engineering

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