Contribution of intermediate filaments to cell stiffness

Ning Wang, Dimitrijie Stamenovic

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The contribution of intermediate filaments to the steady mechanical response of adherent cells was assessed by measuring stiffness in wild-type and vimentin deficient fibroblasts using magnetic twisting cytometry. It was found that in the given range of applied stress, the wild-type cells exhibited greater stiffening than the vimentin-deficient cells. This shows that intermediate filaments contribute to strain-induced stiffening response of adherent cells.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PublisherIEEE
Number of pages1
ISBN (Print)0780356756
StatePublished - Dec 1 1999
Externally publishedYes
EventProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA
Duration: Oct 13 1999Oct 16 1999

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume1
ISSN (Print)0589-1019

Other

OtherProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
CityAtlanta, GA, USA
Period10/13/9910/16/99

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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  • Cite this

    Wang, N., & Stamenovic, D. (1999). Contribution of intermediate filaments to cell stiffness. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; Vol. 1). IEEE.