The projected index computed tomography (PICT) imaging modality provides a computationally reconstructed image of optical index of refraction that is free from spatial distortions. Current implementation using standard filtered backprojection techniques contain linear artifacts resulting from beam path refraction at boundaries with a significant index change. We present the implementation of a least-squares solution whereby every projection datum is assigned a confidence weight, affecting the magnitude of its inclusion into the reconstructed image. The algorithm is shown to significantly reduce artifacts, hence increasing system sensitivity while maintaining spatial accuracy.

Original languageEnglish (US)
Title of host publication2004 2nd IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationMacro to Nano
Number of pages4
StatePublished - 2004
Event2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA, United States
Duration: Apr 15 2004Apr 18 2004


Other2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Country/TerritoryUnited States
CityArlington, VA

ASJC Scopus subject areas

  • Engineering(all)


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