Construction, release and cellular imaging application of triethylamine-responsive fluorescent quantum dots based on supramolecular self-assembly

Yunfeng Shi, Mengyue Wang, Linzhu Zhou, Xueqi Shen, Jinhao Wang, Nannan Mo, Guo Zhao, Su Yang, Xinyuan Zhu, Andrew M. Smith

Research output: Contribution to journalArticlepeer-review

Abstract

A new strategy for the construction, release and cellular imaging application of triethylamine-responsive fluorescent quantum dots (QDs) based on supramolecular self-assembly has been described. The supramolecular self-assembly (HPEI/SA), which was constructed through the electrostatic interactions between terminal amine groups of hyperbranched polyethylenimines (HPEI) and carboxylic acid groups of stearic acid (SA), first captured aqueous Zn2+ ions into the hydrophilic dendritic core and subsequently encapsulated QDs/S2- by the complexation interactions and reactions between Zn2+ and S2- on QDs. Due to the pH-responsive property of the HPEI/SA supramolecular self-assembly, the fluorescence of encapsulated QDs is sensitive to the triethylamine/SA mole ratio, and the encapsulated QDs can be released to the aqueous phase by cleaving HPEI/SA. The resulting fluorescent QDs/HPEI nanocomposites show promising prospects in bioimaging.

Original languageEnglish (US)
Article number110353
JournalEuropean Polymer Journal
Volume148
DOIs
StatePublished - Apr 5 2021

Keywords

  • Bioimaging
  • Release
  • Supramolecular self-assembly
  • Triethylamine-responsive fluorescent quantum dots

ASJC Scopus subject areas

  • General Physics and Astronomy
  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

Fingerprint

Dive into the research topics of 'Construction, release and cellular imaging application of triethylamine-responsive fluorescent quantum dots based on supramolecular self-assembly'. Together they form a unique fingerprint.

Cite this