Constructing disease network and temporal progression model via context-sensitive hawkes process

Edward Choi, Nan Du, Robert Chen, Le Song, Jimeng Sun

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Modeling disease relationships and temporal progression are two key problems in health analytics, which have not been studied together due to data and technical challenges. Thanks to the increasing adoption of Electronic Health Records (EHR), rich patient information is being collected over time. Using EHR data as input, we propose a multivariate context-sensitive Hawkes process or cHawkes, which simultaneously infers the disease relationship network and models temporal progression of patients. Besides learning disease network and temporal progression model, cHawkes is able to predict when a specific patient might have other related diseases in future given the patient history, which in turn can have many potential applications in predictive health analytics, public health policy development and customized patient care. Extensive experiments on real EHR data demonstrate that cHawkes not only can uncover meaningful disease relations and model accurate temporal progression of patients, but also has significantly better predictive performance compared to several baseline models.

Original languageEnglish (US)
Title of host publicationProceedings - 15th IEEE International Conference on Data Mining, ICDM 2015
EditorsCharu Aggarwal, Zhi-Hua Zhou, Alexander Tuzhilin, Hui Xiong, Xindong Wu
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages721-726
Number of pages6
ISBN (Electronic)9781467395038
DOIs
StatePublished - Jan 5 2016
Externally publishedYes
Event15th IEEE International Conference on Data Mining, ICDM 2015 - Atlantic City, United States
Duration: Nov 14 2015Nov 17 2015

Publication series

NameProceedings - IEEE International Conference on Data Mining, ICDM
Volume2016-January
ISSN (Print)1550-4786

Other

Other15th IEEE International Conference on Data Mining, ICDM 2015
Country/TerritoryUnited States
CityAtlantic City
Period11/14/1511/17/15

Keywords

  • Disease Prediction
  • Disease Relation
  • EHR
  • Hawkes Process
  • Health Analytics
  • Point Process

ASJC Scopus subject areas

  • General Engineering

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