Computational fluid dynamics model for optimal flow injection analysis biosensor design

S. Vermeir, P. Verboven, Y. T. Atalay, B. M. Nicolaï, J. Lammertyn, J. Irudayaraj

Research output: Chapter in Book/Report/Conference proceedingConference contribution


This paper presents the optimization of a flow injection analysis (FIA) biosensor with respect to its design and operational parameters such as flow cell geometry, microfluidic channel dimensions, and flow rate. Since it is time consuming and costly to investigate the effect of each factor on the biosensor performance by building it, Computational Fluid Dynamics (CFD) theory is presented as a great tool for finding optimal parameter values. This modeling approach has a high potential in the design of high accuracy FIA-biosensors, regardless of the chosen enzyme substrate system. As an example the optimal design for a glucose/glucose oxidase FIA biosensor is calculated with the CFD theory.

Original languageEnglish (US)
Title of host publicationProceedings of the Fourth IEEE Conference on Sensors 2005
Number of pages4
StatePublished - 2005
Externally publishedYes
EventFourth IEEE Conference on Sensors 2005 - Irvine, CA, United States
Duration: Oct 31 2005Nov 3 2005

Publication series

NameProceedings of IEEE Sensors


OtherFourth IEEE Conference on Sensors 2005
Country/TerritoryUnited States
CityIrvine, CA

ASJC Scopus subject areas

  • Electrical and Electronic Engineering


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