Computational fluid dynamics model for optimal flow injection analysis biosensor design

S. Vermeir, P. Verboven, Y. T. Atalay, B. M. Nicolaï, J. Lammertyn, Joseph Maria Kumar Irudayaraj

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper presents the optimization of a flow injection analysis (FIA) biosensor with respect to its design and operational parameters such as flow cell geometry, microfluidic channel dimensions, and flow rate. Since it is time consuming and costly to investigate the effect of each factor on the biosensor performance by building it, Computational Fluid Dynamics (CFD) theory is presented as a great tool for finding optimal parameter values. This modeling approach has a high potential in the design of high accuracy FIA-biosensors, regardless of the chosen enzyme substrate system. As an example the optimal design for a glucose/glucose oxidase FIA biosensor is calculated with the CFD theory.

Original languageEnglish (US)
Title of host publicationProceedings of the Fourth IEEE Conference on Sensors 2005
Pages365-368
Number of pages4
Volume2005
DOIs
StatePublished - 2005
Externally publishedYes
EventFourth IEEE Conference on Sensors 2005 - Irvine, CA, United States
Duration: Oct 31 2005Nov 3 2005

Other

OtherFourth IEEE Conference on Sensors 2005
CountryUnited States
CityIrvine, CA
Period10/31/0511/3/05

Fingerprint

Biosensors
Dynamic models
Computational fluid dynamics
Glucose oxidase
Microfluidics
Glucose
Enzymes
Flow rate
Geometry
Substrates

ASJC Scopus subject areas

  • Engineering (miscellaneous)
  • Electrical and Electronic Engineering

Cite this

Vermeir, S., Verboven, P., Atalay, Y. T., Nicolaï, B. M., Lammertyn, J., & Irudayaraj, J. M. K. (2005). Computational fluid dynamics model for optimal flow injection analysis biosensor design. In Proceedings of the Fourth IEEE Conference on Sensors 2005 (Vol. 2005, pp. 365-368). [1597712] https://doi.org/10.1109/ICSENS.2005.1597712

Computational fluid dynamics model for optimal flow injection analysis biosensor design. / Vermeir, S.; Verboven, P.; Atalay, Y. T.; Nicolaï, B. M.; Lammertyn, J.; Irudayaraj, Joseph Maria Kumar.

Proceedings of the Fourth IEEE Conference on Sensors 2005. Vol. 2005 2005. p. 365-368 1597712.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Vermeir, S, Verboven, P, Atalay, YT, Nicolaï, BM, Lammertyn, J & Irudayaraj, JMK 2005, Computational fluid dynamics model for optimal flow injection analysis biosensor design. in Proceedings of the Fourth IEEE Conference on Sensors 2005. vol. 2005, 1597712, pp. 365-368, Fourth IEEE Conference on Sensors 2005, Irvine, CA, United States, 10/31/05. https://doi.org/10.1109/ICSENS.2005.1597712
Vermeir S, Verboven P, Atalay YT, Nicolaï BM, Lammertyn J, Irudayaraj JMK. Computational fluid dynamics model for optimal flow injection analysis biosensor design. In Proceedings of the Fourth IEEE Conference on Sensors 2005. Vol. 2005. 2005. p. 365-368. 1597712 https://doi.org/10.1109/ICSENS.2005.1597712
Vermeir, S. ; Verboven, P. ; Atalay, Y. T. ; Nicolaï, B. M. ; Lammertyn, J. ; Irudayaraj, Joseph Maria Kumar. / Computational fluid dynamics model for optimal flow injection analysis biosensor design. Proceedings of the Fourth IEEE Conference on Sensors 2005. Vol. 2005 2005. pp. 365-368
@inproceedings{20f10fd3ef4f4ddc807e8f1c7dd1f355,
title = "Computational fluid dynamics model for optimal flow injection analysis biosensor design",
abstract = "This paper presents the optimization of a flow injection analysis (FIA) biosensor with respect to its design and operational parameters such as flow cell geometry, microfluidic channel dimensions, and flow rate. Since it is time consuming and costly to investigate the effect of each factor on the biosensor performance by building it, Computational Fluid Dynamics (CFD) theory is presented as a great tool for finding optimal parameter values. This modeling approach has a high potential in the design of high accuracy FIA-biosensors, regardless of the chosen enzyme substrate system. As an example the optimal design for a glucose/glucose oxidase FIA biosensor is calculated with the CFD theory.",
author = "S. Vermeir and P. Verboven and Atalay, {Y. T.} and Nicola{\"i}, {B. M.} and J. Lammertyn and Irudayaraj, {Joseph Maria Kumar}",
year = "2005",
doi = "10.1109/ICSENS.2005.1597712",
language = "English (US)",
isbn = "0780390563",
volume = "2005",
pages = "365--368",
booktitle = "Proceedings of the Fourth IEEE Conference on Sensors 2005",

}

TY - GEN

T1 - Computational fluid dynamics model for optimal flow injection analysis biosensor design

AU - Vermeir, S.

AU - Verboven, P.

AU - Atalay, Y. T.

AU - Nicolaï, B. M.

AU - Lammertyn, J.

AU - Irudayaraj, Joseph Maria Kumar

PY - 2005

Y1 - 2005

N2 - This paper presents the optimization of a flow injection analysis (FIA) biosensor with respect to its design and operational parameters such as flow cell geometry, microfluidic channel dimensions, and flow rate. Since it is time consuming and costly to investigate the effect of each factor on the biosensor performance by building it, Computational Fluid Dynamics (CFD) theory is presented as a great tool for finding optimal parameter values. This modeling approach has a high potential in the design of high accuracy FIA-biosensors, regardless of the chosen enzyme substrate system. As an example the optimal design for a glucose/glucose oxidase FIA biosensor is calculated with the CFD theory.

AB - This paper presents the optimization of a flow injection analysis (FIA) biosensor with respect to its design and operational parameters such as flow cell geometry, microfluidic channel dimensions, and flow rate. Since it is time consuming and costly to investigate the effect of each factor on the biosensor performance by building it, Computational Fluid Dynamics (CFD) theory is presented as a great tool for finding optimal parameter values. This modeling approach has a high potential in the design of high accuracy FIA-biosensors, regardless of the chosen enzyme substrate system. As an example the optimal design for a glucose/glucose oxidase FIA biosensor is calculated with the CFD theory.

UR - http://www.scopus.com/inward/record.url?scp=33847299565&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33847299565&partnerID=8YFLogxK

U2 - 10.1109/ICSENS.2005.1597712

DO - 10.1109/ICSENS.2005.1597712

M3 - Conference contribution

AN - SCOPUS:33847299565

SN - 0780390563

SN - 9780780390560

VL - 2005

SP - 365

EP - 368

BT - Proceedings of the Fourth IEEE Conference on Sensors 2005

ER -