Compounds and methods for treatment of cancer and modulation of programmed cell death for melanoma and other cancer cells

Brittany J Allen; Karson S Putt; Vitaliy Nesterenko; Paul J Hergenrother; Benjamin Leslie; Robin S Dothager

Compounds and methods for treatment of cancer and modulation of programmed cell death for melanoma and other cancer cells

Brittany J Allen (Inventor), Karson S Putt (Inventor), Vitaliy Nesterenko (Inventor), Paul J Hergenrother (Inventor), Benjamin Leslie (Inventor), Robin S Dothager (Inventor)

Research output: Patent

Abstract

Compounds and related methods for synthesis, and the use of compounds and combination therapies for the treatment of cancer and modulation of apoptosis in cells are disclosed. The generation of synthetic combinatorial libraries and the evaluation of library member compounds regarding induction of apoptosis selectively in cancer cells are disclosed. Compounds, methods of making the compounds, and therapeutic methods with application against breast cancer cells, melanoma cancer cells, colon cancer cells, and other cancer cells are described.

Original language	English (US)
U.S. patent number	7632972
Filing date	10/27/04
State	Published - Dec 15 2009

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title = "Compounds and methods for treatment of cancer and modulation of programmed cell death for melanoma and other cancer cells",

abstract = "Compounds and related methods for synthesis, and the use of compounds and combination therapies for the treatment of cancer and modulation of apoptosis in cells are disclosed. The generation of synthetic combinatorial libraries and the evaluation of library member compounds regarding induction of apoptosis selectively in cancer cells are disclosed. Compounds, methods of making the compounds, and therapeutic methods with application against breast cancer cells, melanoma cancer cells, colon cancer cells, and other cancer cells are described.",

author = "Allen, {Brittany J} and Putt, {Karson S} and Vitaliy Nesterenko and Hergenrother, {Paul J} and Benjamin Leslie and Dothager, {Robin S}",

note = "STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT This invention was made, at least in part, with government support under Grant Number 0134779 awarded by the National Science Foundation. The government has certain rights in the invention.; 7632972",

year = "2009",

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day = "15",

language = "English (US)",

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TY - PAT

T1 - Compounds and methods for treatment of cancer and modulation of programmed cell death for melanoma and other cancer cells

AU - Allen, Brittany J

AU - Putt, Karson S

AU - Nesterenko, Vitaliy

AU - Hergenrother, Paul J

AU - Leslie, Benjamin

AU - Dothager, Robin S

N1 - STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT This invention was made, at least in part, with government support under Grant Number 0134779 awarded by the National Science Foundation. The government has certain rights in the invention.

PY - 2009/12/15

Y1 - 2009/12/15

N2 - Compounds and related methods for synthesis, and the use of compounds and combination therapies for the treatment of cancer and modulation of apoptosis in cells are disclosed. The generation of synthetic combinatorial libraries and the evaluation of library member compounds regarding induction of apoptosis selectively in cancer cells are disclosed. Compounds, methods of making the compounds, and therapeutic methods with application against breast cancer cells, melanoma cancer cells, colon cancer cells, and other cancer cells are described.

AB - Compounds and related methods for synthesis, and the use of compounds and combination therapies for the treatment of cancer and modulation of apoptosis in cells are disclosed. The generation of synthetic combinatorial libraries and the evaluation of library member compounds regarding induction of apoptosis selectively in cancer cells are disclosed. Compounds, methods of making the compounds, and therapeutic methods with application against breast cancer cells, melanoma cancer cells, colon cancer cells, and other cancer cells are described.

M3 - Patent

M1 - 7632972

Y2 - 2004/10/27

ER -

Compounds and methods for treatment of cancer and modulation of programmed cell death for melanoma and other cancer cells

Abstract

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