Compounds and methods for the treatment of cancer

Karson S Putt; Ted Tarasow; Joseph S. Sandhorst; Paul J Hergenrother; Valerie E. Fako; Quinn P. Peterson

Compounds and methods for the treatment of cancer

Karson S Putt (Inventor), Ted Tarasow (Inventor), Joseph S. Sandhorst (Inventor), Paul J Hergenrother (Inventor), Valerie E. Fako (Inventor), Quinn P. Peterson (Inventor)

Research output: Patent

Abstract

Compositions and methods relating to induction of cell death such as in cancer cells are disclosed. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds in connection with modification of procaspases such as procaspase-3 are disclosed. In various embodiments, the compounds and compositions are capable of activation of procaspase-3.

Original language	English (US)
U.S. patent number	11612598
Filing date	12/21/18
State	Published - Mar 28 2023

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title = "Compounds and methods for the treatment of cancer",

abstract = "Compositions and methods relating to induction of cell death such as in cancer cells are disclosed. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds in connection with modification of procaspases such as procaspase-3 are disclosed. In various embodiments, the compounds and compositions are capable of activation of procaspase-3.",

author = "Putt, {Karson S} and Ted Tarasow and Sandhorst, {Joseph S.} and Hergenrother, {Paul J} and Fako, {Valerie E.} and Peterson, {Quinn P.}",

year = "2023",

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day = "28",

language = "English (US)",

type = "Patent",

note = "11612598",

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TY - PAT

T1 - Compounds and methods for the treatment of cancer

AU - Putt, Karson S

AU - Tarasow, Ted

AU - Sandhorst, Joseph S.

AU - Hergenrother, Paul J

AU - Fako, Valerie E.

AU - Peterson, Quinn P.

PY - 2023/3/28

Y1 - 2023/3/28

N2 - Compositions and methods relating to induction of cell death such as in cancer cells are disclosed. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds in connection with modification of procaspases such as procaspase-3 are disclosed. In various embodiments, the compounds and compositions are capable of activation of procaspase-3.

AB - Compositions and methods relating to induction of cell death such as in cancer cells are disclosed. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds in connection with modification of procaspases such as procaspase-3 are disclosed. In various embodiments, the compounds and compositions are capable of activation of procaspase-3.

M3 - Patent

M1 - 11612598

Y2 - 2018/12/21

ER -

Compounds and methods for the treatment of cancer

Abstract

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