Compositions and methods for reducing the risk of agent-induced liver toxicity

Timothy A Garrow (Inventor), Hong-Hsing Liu (Inventor), Gary Peltz (Inventor), Guochun Liao (Inventor)

Research output: Patent

Abstract

The present disclosure relates generally to a pharmaceutical compositions and methods of reducing acetaminophen-induced liver toxicity. The disclosure includes pharmaceutical compositions including acetaminophen and one or more components selected from S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof. The disclosure also relates to methods of reducing acetaminophen-induced liver toxicity in a subject by administering or co-administering one or more of S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof, with acetaminophen to a subject.
Original languageEnglish (US)
U.S. patent number8685956
Filing date9/16/10
StatePublished - Apr 1 2014

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