Compositions and methods comprising long-chain, straight-chain 2-amino-3-hydroxyalkanes

Glynn Faircloth (Inventor), Dolores Garcia Gravalos (Inventor), Kenneth L. Rinehart (Inventor), Nancy L Fregeau Gallagher (Inventor), Robert A Warwick (Inventor), Jesus Avila (Inventor)

Research output: Patent


Investigation of the activity of extracts of the clam Spisula polynyma has led to antitumor long-chain, straight-chain alkane or alkene compounds which have a 2-amino group and a 3-hydroxy group. The present invention is directed to compositions and methods comprising an isolated and purified long-chain, straight-chain 2-amino-3-hydroxyalkane, or prodrug thereof, and a pharmaceutically acceptable carrier, wherein the carbon chain in the long-chain, straight-chain 2-amino-3-hydroxyalkane is C16–C24.
Original languageEnglish (US)
U.S. patent number7109244
Filing date10/23/03
StatePublished - Sep 19 2006


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