Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism

Keyphrases

• Complex Structure 100%
• Catalytic Mechanism 100%
• Substrate Analog 100%
• Farnesyl 100%
• 3-phosphoglycerate 100%
• Geranylgeranyl Pyrophosphate 100%
• Complex Crystal Structure 66%
• Prenyltransferase 66%
• Condensation 33%
• Antibiotics 33%
• Elimination Method 33%
• Preferred Sites 33%
• Phosphoglycerate 33%
• Prenyl 33%
• Alkyl Polyglucoside 33%
• Moenomycin 33%
• Branched Oligosaccharides 33%
• Long-chain Alkyl 33%
• Sequential Ionization 33%
• Carbocation Intermediates 33%

Biochemistry, Genetics and Molecular Biology

• Substrate Analog 100%
• Catalytic Mechanism 100%
• Pyrophosphate 100%
• Crystal Structure 66%
• Conformation 33%
• Enzyme 33%
• Oligosaccharide 33%
• Glycoside 33%
• Chlordiazepoxide 33%

Chemistry

• 3-Phosphoglycerate 100%
• Crystal Structure 66%
• Condensation 33%
• Oligosaccharide 33%
• Glycoside 33%
• Carbocation 33%
• Phosphoglycerate 33%
• formation 33%
• Chlordiazepoxide 33%