TY - GEN
T1 - Complex shear modulus of thermally-damaged liver
AU - Orescanin, Marko
AU - Qayyum, Muqeem A.
AU - Toohey, Kathleen S.
AU - Insana, Michael F.
PY - 2009
Y1 - 2009
N2 - The complex shear modulus of fresh and thermally damaged porcine liver has been measured, in vitro, using an ultrasonic shear wave imaging technique. Measurements were compared to two constitutive models, Kelvin-Voigt and Zener, to estimate the complex modulus of liver for shear wave frequencies between 50 and 300 Hz. An axially vibrated needle placed in the liver excites harmonic shear waves that are imaged using a pulsed Doppler technique. Liver heated to 47°C for 90 min was found to have little measurable cellular damage, and yet the elastic shear modulus increased by a factor of two and the viscous shear modulus increased by a factor of three in this frequency range. These observations imply that elastic properties, especially the viscous shear modulus, may be a sensitive indicator of thermal damage. Also, within the testing bandwidth for shear waves, the Zener model represented the data better than the Kelvin-Voigt model.
AB - The complex shear modulus of fresh and thermally damaged porcine liver has been measured, in vitro, using an ultrasonic shear wave imaging technique. Measurements were compared to two constitutive models, Kelvin-Voigt and Zener, to estimate the complex modulus of liver for shear wave frequencies between 50 and 300 Hz. An axially vibrated needle placed in the liver excites harmonic shear waves that are imaged using a pulsed Doppler technique. Liver heated to 47°C for 90 min was found to have little measurable cellular damage, and yet the elastic shear modulus increased by a factor of two and the viscous shear modulus increased by a factor of three in this frequency range. These observations imply that elastic properties, especially the viscous shear modulus, may be a sensitive indicator of thermal damage. Also, within the testing bandwidth for shear waves, the Zener model represented the data better than the Kelvin-Voigt model.
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U2 - 10.1109/ULTSYM.2009.5441919
DO - 10.1109/ULTSYM.2009.5441919
M3 - Conference contribution
AN - SCOPUS:77952864702
SN - 9781424443895
T3 - Proceedings - IEEE Ultrasonics Symposium
SP - 127
EP - 130
BT - 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2009 IEEE International Ultrasonics Symposium, IUS 2009
Y2 - 20 September 2009 through 23 September 2009
ER -