Complex interactions of circadian rhythms, eating behaviors, and the gastrointestinal microbiota and their potential impact on health

Jennifer L Kaczmarek, Sharon V Thompson, Hannah D Holscher

Research output: Contribution to journalArticlepeer-review

Abstract

Human health is intricately intertwined with the composition and function of the trillions of microorganisms that make up the gastrointestinal (GI) microbiome. The GI microbiome is essentially a microbial organ that provides metabolic, immunologic, and protective functions for the host. Habitual diet, changes in macronutrient composition, and consumption of nondigestible dietary fibers have all been shown to impact the human GI microbiome. Intriguingly, the impact of diet on the microbiome may be related not only to what humans eat but also to the timing of food consumption. Emerging preclinical research suggests that gut microbes experience diurnal rhythms, and the health effects of eating patterns, including time-restricted feeding and meal frequency, may be related to the GI microbiome. Herein, the complex connections among circadian rhythms, eating behaviors, the GI microbiome, and health are reviewed, highlighting the need for additional translational research in this area.

Original languageEnglish (US)
Pages (from-to)673-682
Number of pages10
JournalNutrition Reviews
Volume75
Issue number9
DOIs
StatePublished - Sep 1 2017

Keywords

  • circadian rhythm
  • eating frequency
  • eating patterns
  • jet lag
  • microbiome
  • shift work
  • time-restricted feeding
  • Time-restricted feeding
  • Circadian rhythm
  • Eating frequency
  • Shift work
  • Jet lag
  • Eating patterns
  • Microbiome

ASJC Scopus subject areas

  • Nutrition and Dietetics
  • Medicine (miscellaneous)

Fingerprint Dive into the research topics of 'Complex interactions of circadian rhythms, eating behaviors, and the gastrointestinal microbiota and their potential impact on health'. Together they form a unique fingerprint.

Cite this