Comparison of data-acquisition designs for single-shot edge-illumination X-ray phase-contrast tomography

Yujia Chen, Weimin Zhou, Charlotte K. Hagen, Alessandro Olivo, Mark A. Anastasio

Research output: Contribution to journalArticlepeer-review


Edge-illumination X-ray phase-contrast tomography (EIXPCT) is an emerging technique that enables practical phase-contrast imaging with laboratory-based X-ray sources. A joint reconstruction method was proposed for reconstructing EIXPCT images, enabling novel flexible data-acquisition designs. However, only limited efforts have been devoted to optimizing data-acquisition designs for use with the joint reconstruction method. In this study, several promising designs are introduced, such as the constant aperture position (CAP) strategy and the alternating aperture position (AAP) strategy covering different angular ranges. In computer-simulation studies, these designs are analyzed and compared. Experimental data are employed to test the designs in real-world applications. All candidate designs are also compared for their implementation complexity. The tradeoff between data-acquisition time and image quality is discussed.

Original languageEnglish (US)
Pages (from-to)1-19
Number of pages19
JournalOptics Express
Issue number1
StatePublished - 2020

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics


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