Comparative genomics of closely related salmonellae

Robert A. Edwards, Gary J. Olsen, Stanley R. Maloy

Research output: Contribution to journalReview article

Abstract

As the number of completed genome sequences increases, there is increasing emphasis on comparative genomic analysis of closely related organisms. Comparison of the similarities and differences between the five publicly available Salmonella genome sequences reveals extensive sequence conservation among the Salmonella serovars. However, horizontal gene transfer has provided each genome with between 10% and 12% of unique DNA. Genome comparisons of the closely related salmonellae emphasize the insights that can be gleaned from sequencing genomes of a single species.

Original languageEnglish (US)
Pages (from-to)94-99
Number of pages6
JournalTrends in Microbiology
Volume10
Issue number2
DOIs
StatePublished - Feb 1 2002

Fingerprint

Genomics
Salmonella
Genome
Horizontal Gene Transfer
DNA

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology

Cite this

Comparative genomics of closely related salmonellae. / Edwards, Robert A.; Olsen, Gary J.; Maloy, Stanley R.

In: Trends in Microbiology, Vol. 10, No. 2, 01.02.2002, p. 94-99.

Research output: Contribution to journalReview article

Edwards, Robert A. ; Olsen, Gary J. ; Maloy, Stanley R. / Comparative genomics of closely related salmonellae. In: Trends in Microbiology. 2002 ; Vol. 10, No. 2. pp. 94-99.
@article{989414edf38c4e0a9a5bec926345f51b,
title = "Comparative genomics of closely related salmonellae",
abstract = "As the number of completed genome sequences increases, there is increasing emphasis on comparative genomic analysis of closely related organisms. Comparison of the similarities and differences between the five publicly available Salmonella genome sequences reveals extensive sequence conservation among the Salmonella serovars. However, horizontal gene transfer has provided each genome with between 10{\%} and 12{\%} of unique DNA. Genome comparisons of the closely related salmonellae emphasize the insights that can be gleaned from sequencing genomes of a single species.",
author = "Edwards, {Robert A.} and Olsen, {Gary J.} and Maloy, {Stanley R.}",
year = "2002",
month = "2",
day = "1",
doi = "10.1016/S0966-842X(01)02293-4",
language = "English (US)",
volume = "10",
pages = "94--99",
journal = "Trends in Microbiology",
issn = "0966-842X",
publisher = "Elsevier Limited",
number = "2",

}

TY - JOUR

T1 - Comparative genomics of closely related salmonellae

AU - Edwards, Robert A.

AU - Olsen, Gary J.

AU - Maloy, Stanley R.

PY - 2002/2/1

Y1 - 2002/2/1

N2 - As the number of completed genome sequences increases, there is increasing emphasis on comparative genomic analysis of closely related organisms. Comparison of the similarities and differences between the five publicly available Salmonella genome sequences reveals extensive sequence conservation among the Salmonella serovars. However, horizontal gene transfer has provided each genome with between 10% and 12% of unique DNA. Genome comparisons of the closely related salmonellae emphasize the insights that can be gleaned from sequencing genomes of a single species.

AB - As the number of completed genome sequences increases, there is increasing emphasis on comparative genomic analysis of closely related organisms. Comparison of the similarities and differences between the five publicly available Salmonella genome sequences reveals extensive sequence conservation among the Salmonella serovars. However, horizontal gene transfer has provided each genome with between 10% and 12% of unique DNA. Genome comparisons of the closely related salmonellae emphasize the insights that can be gleaned from sequencing genomes of a single species.

UR - http://www.scopus.com/inward/record.url?scp=0036468520&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036468520&partnerID=8YFLogxK

U2 - 10.1016/S0966-842X(01)02293-4

DO - 10.1016/S0966-842X(01)02293-4

M3 - Review article

C2 - 11827811

AN - SCOPUS:0036468520

VL - 10

SP - 94

EP - 99

JO - Trends in Microbiology

JF - Trends in Microbiology

SN - 0966-842X

IS - 2

ER -