Compact label-free biosensor using VCSEL-based measurement system

Carlos F.R. Mateus, Michael C.Y. Huang, Peter Li, Brian T. Cunningham, Connie J. Chang-Hasnain

Research output: Contribution to journalArticlepeer-review


We report an ultracompact label-free biosensor that uses a vertical-cavity surface-emitting laser (VCSEL)-based measurement system for the characterization of biomolecular interactions. It consists of a VCSEL, a plastic guided-mode resonant filter, and two p-i-n detectors. The system has demonstrated very high sensitivity to molecules on top of the sensor.

Original languageEnglish (US)
Pages (from-to)1712-1714
Number of pages3
JournalIEEE Photonics Technology Letters
Issue number7
StatePublished - Jul 2004
Externally publishedYes

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Electrical and Electronic Engineering


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