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Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase

  • Michelle Letarte
  • , Sonia Vera
  • , Rosette Tran
  • , Jane B.L. Addis
  • , Russell J. Onizuka
  • , Elizabeth J. Quackenbush
  • , C. Victor Jongeneel
  • , Roderick R. McInnesi

Research output: Contribution to journalArticlepeer-review

Abstract

We purified CALLA from human kidney and isolated a cDNA clone reactive with two oligonucleotide probes corresponding to two distinct peptides. The amino acid sequence translated from the CALLA cDNA revealed 100% identity with that of human neutral endopeptidase (NEP, enkephalinase). The distributions of CALLA antigen and NEP in normal tissues are similar.

Original languageEnglish (US)
Pages (from-to)1247-1253
Number of pages7
JournalJournal of Experimental Medicine
Volume168
Issue number4
DOIs
StatePublished - Oct 1 1988
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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