Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase

M. Letarte, S. Vera, R. Tran, J. B L Addis, R. J. Onizuka, E. J. Quackenbush, C. V. Jongeneel, R. R. McInnes

Research output: Contribution to journalArticlepeer-review

Abstract

We purified CALLA from human kidney and isolated a cDNA clone reactive with two oligonucleotide probes corresponding to two distinct peptides. The amino acid sequence translated from the CALLA cDNA revealed 100% identity with that of human neutral endopeptidase (NEP, enkephalinase). The distributions of CALLA antigen and NEP in normal tissues are similar.

Original languageEnglish (US)
Pages (from-to)1247-1253
Number of pages7
JournalJournal of Experimental Medicine
Volume168
Issue number4
StatePublished - 1988

ASJC Scopus subject areas

  • Immunology

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