Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase

Michelle Letarte, Sonia Vera, Rosette Tran, Jane B.L. Addis, Russell J. Onizuka, Elizabeth J. Quackenbush, C. Victor Jongeneel, Roderick R. McInnesi

Research output: Contribution to journalArticlepeer-review


We purified CALLA from human kidney and isolated a cDNA clone reactive with two oligonucleotide probes corresponding to two distinct peptides. The amino acid sequence translated from the CALLA cDNA revealed 100% identity with that of human neutral endopeptidase (NEP, enkephalinase). The distributions of CALLA antigen and NEP in normal tissues are similar.

Original languageEnglish (US)
Pages (from-to)1247-1253
Number of pages7
JournalJournal of Experimental Medicine
Issue number4
StatePublished - Oct 1 1988
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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