Abstract
Two approaches were used to synthesize site specific probes which incorporate both fluorophores and the 1.4 nm Nanogold gold particle. One method involves the covalent linkage of the Nanogold particle to Hoescht-33258, a fluorescent dye which is specific for AT-rich regions of double stranded DNA. In the second approach, a label was prepared which consists of a small number of fluorescein groups and the Nanogold particle. Labeled peptides were separated from unbound peptide by gel filtration.
| Original language | English (US) |
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| Pages | 176-177 |
| Number of pages | 2 |
| State | Published - 1994 |
| Externally published | Yes |
| Event | Proceedings of the 52nd Annual Meeting of the Microscopy Society of America - New Orleans, LA, USA Duration: Jul 31 1994 → Aug 5 1994 |
Other
| Other | Proceedings of the 52nd Annual Meeting of the Microscopy Society of America |
|---|---|
| City | New Orleans, LA, USA |
| Period | 7/31/94 → 8/5/94 |
ASJC Scopus subject areas
- General Engineering