Abstract

A simple phenomenological model predicting the hot and cold denaturation of polysoaps is presented. Polysoaps are flexible water-soluble polymers that incorporate, at intervals, covalently bound amphiphiles. In water, these self-assemble into intrachain micelles, thus giving rise to hierarchical self-organization. This structure is predicted to denature, to disassemble, both upon heating and upon cooling. It is possible to narrow the stability range of the intrachain structure by increasing the length of the spacer chain joining the amphiphilic monomers. A similar erect may influence the stability range of protein-polymer conjugates and certain glycosylated proteins.

Original languageEnglish (US)
Pages (from-to)2368-2374
Number of pages7
JournalMacromolecules
Volume31
Issue number7
DOIs
StatePublished - Apr 7 1998

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Denaturation
Polymers
Proteins
Amphiphiles
Water
Micelles
Joining
Monomers
Cooling
Heating

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Inorganic Chemistry
  • Materials Chemistry

Cite this

Cold and hot denaturation of polysoaps. / Leckband, Deborah E; Borisov, O. V.; Halperin, A.

In: Macromolecules, Vol. 31, No. 7, 07.04.1998, p. 2368-2374.

Research output: Contribution to journalArticle

Leckband, DE, Borisov, OV & Halperin, A 1998, 'Cold and hot denaturation of polysoaps', Macromolecules, vol. 31, no. 7, pp. 2368-2374. https://doi.org/10.1021/ma971509q
Leckband, Deborah E ; Borisov, O. V. ; Halperin, A. / Cold and hot denaturation of polysoaps. In: Macromolecules. 1998 ; Vol. 31, No. 7. pp. 2368-2374.
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