Coherent light imaging and scattering for biological investigations

Huafeng Ding, Gabriel Popescu

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Quantitative phase imaging (QPI) of live cells has received significant scientific interest over the past decade or so, mainly because it offers structure and dynamics information at the nanometer scale in a completely noninvasive manner. Fourier transform light scattering (FTLS) relies on quantifying the optical phase and amplitude associated with a coherent image field and propagating it numerically to the scattering plane. It combines optical microscopy, holography, and light scattering for studying inhomogeneous and dynamic media. We present recent developments of QPI technology and FTLS for biological system structure and dynamics study. Their applications are classified into static and dynamic according to their temporal selectivity. Several promising prospects are discussed in the summary section.

Original languageEnglish (US)
Title of host publicationCoherent Light Microscopy
Subtitle of host publicationImaging and Quantitative Phase Analysis
EditorsPietro Ferraro, Adam Wax, Zeev Zalevsky
Pages229-265
Number of pages37
Edition1
DOIs
StatePublished - Dec 1 2011

Publication series

NameSpringer Series in Surface Sciences
Number1
Volume46
ISSN (Print)0931-5195

ASJC Scopus subject areas

  • Surfaces, Coatings and Films

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  • Cite this

    Ding, H., & Popescu, G. (2011). Coherent light imaging and scattering for biological investigations. In P. Ferraro, A. Wax, & Z. Zalevsky (Eds.), Coherent Light Microscopy: Imaging and Quantitative Phase Analysis (1 ed., pp. 229-265). (Springer Series in Surface Sciences; Vol. 46, No. 1). https://doi.org/10.1007/978-3-642-15813-1_9