TY - GEN
T1 - Coherent fiber supercontinuum laser for nonlinear biomedical imaging
AU - Tu, Haohua
AU - Liu, Yuan
AU - Liu, Xiaomin
AU - Lægsgaard, Jesper
AU - Turchinovich, Dmitry
AU - Boppart, Stephen A.
PY - 2012
Y1 - 2012
N2 - Nonlinear biomedical imaging has not benefited from the well-known techniques of fiber supercontinuum generation for reasons such as poor coherence (or high noise), insufficient controllability, low spectral power intensity, and inadequate portability. Fortunately, a few techniques involving nonlinear fiber optics and femtosecond fiber laser development have emerged to overcome these critical limitations. These techniques pave the way for conducting point-of-care nonlinear biomedical imaging by a low-maintenance cost-effective coherent fiber supercontinuum laser, which covers a broad emission wavelength of 350-1700 nm. A prototype of this laser has been demonstrated in label-free multimodal nonlinear imaging of cell and tissue samples.
AB - Nonlinear biomedical imaging has not benefited from the well-known techniques of fiber supercontinuum generation for reasons such as poor coherence (or high noise), insufficient controllability, low spectral power intensity, and inadequate portability. Fortunately, a few techniques involving nonlinear fiber optics and femtosecond fiber laser development have emerged to overcome these critical limitations. These techniques pave the way for conducting point-of-care nonlinear biomedical imaging by a low-maintenance cost-effective coherent fiber supercontinuum laser, which covers a broad emission wavelength of 350-1700 nm. A prototype of this laser has been demonstrated in label-free multimodal nonlinear imaging of cell and tissue samples.
KW - femtosecond laser
KW - Multiphoton microscopy
KW - nonlinear fiber optics
KW - photonic crystal fiber
KW - supercontinuum
UR - http://www.scopus.com/inward/record.url?scp=84875928183&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84875928183&partnerID=8YFLogxK
U2 - 10.1117/12.999522
DO - 10.1117/12.999522
M3 - Conference contribution
AN - SCOPUS:84875928183
SN - 9780819493088
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Optics in Health Care and Biomedical Optics V
T2 - Optics in Health Care and Biomedical Optics V
Y2 - 5 November 2012 through 7 November 2012
ER -