Coagulation and fibrinolytic cascades modulator

James H Morrissey; Nicola J Mutch; Stephanie A Smith; Roberto Docampo

Coagulation and fibrinolytic cascades modulator

James H Morrissey (Inventor), Nicola J Mutch (Inventor), Stephanie A Smith (Inventor), Roberto Docampo (Inventor)

Research output: Patent

Abstract

Methods for stopping or slowing bleeding from a wound are provided; these methods include the step of administering a composition comprising a polyphosphate (polyP) to blood from the wound at the site of the wound. Also provided are methods for slowing fibrinolysis and for blocking the action of Tissue Factor Pathway Inhibitor (TFPI) with the use of polyP.

Original language	English (US)
U.S. patent number	9597375
Filing date	10/20/09
State	Published - Mar 21 2017

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title = "Coagulation and fibrinolytic cascades modulator",

abstract = "Methods for stopping or slowing bleeding from a wound are provided; these methods include the step of administering a composition comprising a polyphosphate (polyP) to blood from the wound at the site of the wound. Also provided are methods for slowing fibrinolysis and for blocking the action of Tissue Factor Pathway Inhibitor (TFPI) with the use of polyP.",

author = "Morrissey, {James H} and Mutch, {Nicola J} and Smith, {Stephanie A} and Roberto Docampo",

note = "FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT This application was funded in part under the following research grants and contracts: NIH (NHLBI and NIAID) Grant Nos. P50 HL45402, R01 HL47014, and R01 AI23259. The U.S. Government has certain rights in this invention.; 9597375",

year = "2017",

month = mar,

day = "21",

language = "English (US)",

type = "Patent",

}

TY - PAT

T1 - Coagulation and fibrinolytic cascades modulator

AU - Morrissey, James H

AU - Mutch, Nicola J

AU - Smith, Stephanie A

AU - Docampo, Roberto

N1 - FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT This application was funded in part under the following research grants and contracts: NIH (NHLBI and NIAID) Grant Nos. P50 HL45402, R01 HL47014, and R01 AI23259. The U.S. Government has certain rights in this invention.

PY - 2017/3/21

Y1 - 2017/3/21

N2 - Methods for stopping or slowing bleeding from a wound are provided; these methods include the step of administering a composition comprising a polyphosphate (polyP) to blood from the wound at the site of the wound. Also provided are methods for slowing fibrinolysis and for blocking the action of Tissue Factor Pathway Inhibitor (TFPI) with the use of polyP.

AB - Methods for stopping or slowing bleeding from a wound are provided; these methods include the step of administering a composition comprising a polyphosphate (polyP) to blood from the wound at the site of the wound. Also provided are methods for slowing fibrinolysis and for blocking the action of Tissue Factor Pathway Inhibitor (TFPI) with the use of polyP.

M3 - Patent

M1 - 9597375

Y2 - 2009/10/20

ER -

Coagulation and fibrinolytic cascades modulator

Abstract

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