Coagulation and fibrinolytic cascades modulator

James H Morrissey (Inventor), Nicola J Mutch (Inventor), Stephanie A Smith (Inventor), Roberto Docampo (Inventor)

Research output: Patent


Methods for stopping or slowing bleeding from a wound are provided; these methods include the step of administering a composition comprising a polyphosphate (polyP) to blood from the wound at the site of the wound. Also provided are methods for slowing fibrinolysis and for blocking the action of Tissue Factor Pathway Inhibitor (TFPI) with the use of polyP.
Original languageEnglish (US)
U.S. patent number9597375
Filing date10/20/09
StatePublished - Mar 21 2017


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