Abstract
Clostridium acetobutylicum belongs to a group of Gram-positive and endospore forming anaerobes and is considered to be a model organism for solventogenic clostridia due to its acetone-butanol-ethanol (ABE) fermentation metabolism. This chapter focuses on the physiology of the biphasic fermentative metabolism of C. acetobutylicum, the history of the ABE fermentation, and industrial applications during the past century. Different approaches to improving solvent production and overcoming solvent toxicity utilizing genetic tools developed over the past 20 years are also discussed.
| Original language | English (US) |
|---|---|
| Title of host publication | Encyclopedia of Food Microbiology |
| Subtitle of host publication | Second Edition |
| Publisher | Elsevier Inc. |
| Pages | 449-457 |
| Number of pages | 9 |
| ISBN (Electronic) | 9780123847331 |
| ISBN (Print) | 9780123847300 |
| DOIs | |
| State | Published - Apr 2 2014 |
Keywords
- ABE fermentation
- Acetate
- Acetone
- Acidogenesis
- Butanol
- Butanol tolerance
- Butyrate
- Clostridia
- Clostridium acetobutylicum
- Genetic engineering
- Product recovery
- Solventogenesis
ASJC Scopus subject areas
- General Medicine