Close encounters between active genes in the nucleus

Chien Hui Chuang; Andrew S. Belmont

doi:10.1186/gb-2005-6-11-237

Close encounters between active genes in the nucleus

Research output: Contribution to journal › Short survey › peer-review

Abstract

A recent paper demonstrates that coregulated genes on different chromosomes show surprisingly high frequencies of colocalization within the nucleus; this complements similar results found previously for genes localized tens of megabases apart on a single chromosome. Colocalization could be related to the earlier observation of active genes associating with foci where RNA polymerase II is concentrated.

Original language	English (US)
Article number	237
Journal	Genome biology
Volume	6
Issue number	11
DOIs	https://doi.org/10.1186/gb-2005-6-11-237
State	Published - 2005

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Genetics
Cell Biology

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10.1186/gb-2005-6-11-237

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title = "Close encounters between active genes in the nucleus",

abstract = "A recent paper demonstrates that coregulated genes on different chromosomes show surprisingly high frequencies of colocalization within the nucleus; this complements similar results found previously for genes localized tens of megabases apart on a single chromosome. Colocalization could be related to the earlier observation of active genes associating with foci where RNA polymerase II is concentrated.",

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AB - A recent paper demonstrates that coregulated genes on different chromosomes show surprisingly high frequencies of colocalization within the nucleus; this complements similar results found previously for genes localized tens of megabases apart on a single chromosome. Colocalization could be related to the earlier observation of active genes associating with foci where RNA polymerase II is concentrated.

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Close encounters between active genes in the nucleus

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