Clinical trial of moxidectin oral gel in horses

J. A. DiPietro, D. E. Hutchens, T. F. Lock, K. Walker, A. J. Paul, C. Shipley, D. Rulli

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A clinical trial carried out over 98 days was done to evaluate treatment of horses with moxidectin gel for efficacy as measured by (1) reduction in the production of parasite ova post treatment, (2) a comparison of the posttreatment parasite egg count suppression of moxidectin to ivermectin, and (3) assessment of the field safety, animal acceptance of the moxidectin formulation, and the utility of the moxidectin delivery device. One hundred and fifty Standardbred horses with naturally acquired parasite infections were used in the study. Moxidectin had more prolonged and greater suppressive influence than did ivermectin on reappearance and magnitude of strongyle egg counts post treatment. Differences were not observed between the capability of ivermectin or moxidectin to reduce and suppress low Parascaris equorum egg counts. Adverse reactions to treatments were net observed, and the utility of the moxidectin delivery syringe and animal acceptance of moxidectin treatment were satisfactory.

    Original languageEnglish (US)
    Pages (from-to)167-177
    Number of pages11
    JournalVeterinary parasitology
    Volume72
    Issue number2
    DOIs
    StatePublished - Oct 1997

    Keywords

    • Avermectin
    • Cyanthostomes
    • Equine
    • Ivermectin
    • Moxidectin
    • Parascaris equorum
    • Strongyles

    ASJC Scopus subject areas

    • Parasitology
    • veterinary(all)

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