Abstract
1. 1. Previous studies indicate the β-adrenergic agonist, clenbuterol, does not stimulate porcine adipose tissue lipolysis or cAMP concentration in vitro but increases plasma free fatty acid concentrations when infused, implying an indirect mechanism in vivo. 2. 2. One indirect mechanism is the release of endogenous catecholamines to increase adipose tissue lipolysis and raise plasma free fatty acids. 3. 3. In pigs treated with reserpine to deplete endogenous catecholamines, clenbuterol infusion increased plasma free fatty acids concentration suggesting that this increase in vivo did not result from release of endogenous catecholamines.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 619-622 |
| Number of pages | 4 |
| Journal | Comparative Biochemistry and Physiology. Part C, Comparative |
| Volume | 91 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1988 |
ASJC Scopus subject areas
- Immunology
- Pharmacology
Fingerprint Dive into the research topics of 'Clenbuterol stimulated increase of plasma free fatty acids in reserpinized pigs'. Together they form a unique fingerprint.
Cite this
Hu, C. Y., Novakofski, J., & Mersmann, H. J. (1988). Clenbuterol stimulated increase of plasma free fatty acids in reserpinized pigs. Comparative Biochemistry and Physiology. Part C, Comparative, 91(2), 619-622. https://doi.org/10.1016/0742-8413(88)90088-6