TY - JOUR
T1 - Clenbuterol stimulated increase of plasma free fatty acids in reserpinized pigs
AU - Hu, C. Y.
AU - Novakofski, J.
AU - Mersmann, H. J.
PY - 1988
Y1 - 1988
N2 - 1. 1. Previous studies indicate the β-adrenergic agonist, clenbuterol, does not stimulate porcine adipose tissue lipolysis or cAMP concentration in vitro but increases plasma free fatty acid concentrations when infused, implying an indirect mechanism in vivo. 2. 2. One indirect mechanism is the release of endogenous catecholamines to increase adipose tissue lipolysis and raise plasma free fatty acids. 3. 3. In pigs treated with reserpine to deplete endogenous catecholamines, clenbuterol infusion increased plasma free fatty acids concentration suggesting that this increase in vivo did not result from release of endogenous catecholamines.
AB - 1. 1. Previous studies indicate the β-adrenergic agonist, clenbuterol, does not stimulate porcine adipose tissue lipolysis or cAMP concentration in vitro but increases plasma free fatty acid concentrations when infused, implying an indirect mechanism in vivo. 2. 2. One indirect mechanism is the release of endogenous catecholamines to increase adipose tissue lipolysis and raise plasma free fatty acids. 3. 3. In pigs treated with reserpine to deplete endogenous catecholamines, clenbuterol infusion increased plasma free fatty acids concentration suggesting that this increase in vivo did not result from release of endogenous catecholamines.
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U2 - 10.1016/0742-8413(88)90088-6
DO - 10.1016/0742-8413(88)90088-6
M3 - Article
C2 - 2905978
AN - SCOPUS:0023776091
SN - 0306-4492
VL - 91
SP - 619
EP - 622
JO - Comparative Biochemistry and Physiology. Part C, Comparative
JF - Comparative Biochemistry and Physiology. Part C, Comparative
IS - 2
ER -