Clenbuterol stimulated increase of plasma free fatty acids in reserpinized pigs

C. Y. Hu, J. Novakofski, H. J. Mersmann

Research output: Contribution to journalArticle


1. 1. Previous studies indicate the β-adrenergic agonist, clenbuterol, does not stimulate porcine adipose tissue lipolysis or cAMP concentration in vitro but increases plasma free fatty acid concentrations when infused, implying an indirect mechanism in vivo. 2. 2. One indirect mechanism is the release of endogenous catecholamines to increase adipose tissue lipolysis and raise plasma free fatty acids. 3. 3. In pigs treated with reserpine to deplete endogenous catecholamines, clenbuterol infusion increased plasma free fatty acids concentration suggesting that this increase in vivo did not result from release of endogenous catecholamines.

Original languageEnglish (US)
Pages (from-to)619-622
Number of pages4
JournalComparative Biochemistry and Physiology. Part C, Comparative
Issue number2
StatePublished - 1988

ASJC Scopus subject areas

  • Immunology
  • Pharmacology

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