Chromosomal fragmentation is the major consequence of the rdgB defect in Escherichia coli

Lisa Lukas, Andrei Kuzminov

Research output: Contribution to journalArticlepeer-review

Abstract

The rdgB mutants depend on recombinational repair of double-strand breaks. To assess other consequences of rdgB inactivation in Escherichia coli, we isolated RdgB-dependent mutants. All transposon inserts making cells dependent on RdgB inactivate genes of double-strand break repair, indicating that chromosomal fragmentation is the major consequence of RdgB inactivation.

Original languageEnglish (US)
Pages (from-to)1359-1362
Number of pages4
JournalGenetics
Volume172
Issue number2
DOIs
StatePublished - Feb 2006

ASJC Scopus subject areas

  • Genetics

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