Chromatin immunocapture devices and methods of use

Ryan C Bailey (Inventor), Joshua D Tice (Inventor), Tamas Ordog (Inventor), Jeong Heon Lee (Inventor), Richard M. Graybill (Inventor), Yi Xu (Inventor), Steven R Doonan (Inventor)

Research output: Patent


This application provides fluidic devices, such as microfluidic devices, which can be used for the creation and/or manipulation of droplets in droplet-based microfluidic systems, as well as systems and methods for using the same. The microfluidic devices can be used to generate droplets, extract or inject volume to droplets, and/or split droplets. Also provided are methods for generating nucleosomes, and isolated DNA from nucleosomes (or from non-nucleosomes), for example using the disclosed devices.
Original languageEnglish (US)
U.S. patent number10597698
StatePublished - Mar 24 2020


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