Chitosan/sericin blend membranes for adsorption of bovine serum albumin

Jennifer Runhong Du; Xiao Su; Xianshe Feng

doi:10.1002/cjce.22760

Chitosan/sericin blend membranes for adsorption of bovine serum albumin

Jennifer Runhong Du
, Xiao Su
, Xianshe Feng

Research output: Contribution to journal › Article › peer-review

Abstract

Chitosan/sericin blend membranes for adsorption of bovine serum albumin (BSA) were investigated. A preliminary screening test was carried out to identify a suitable chitosan/sericin blend ratio. The blend membrane with a chitosan/sericin mass ratio of 4:1 was found to have a maximum adsorption capacity (q_m) of 25.3 g/m², which is 45 % greater than the maximum adsorption capacity of the pure chitosan membrane. The adsorption-desorption cycle studies showed that the chitosan/sericin blend affinity membrane could be reused, and over 80 % of the original adsorption capacity was retained after regeneration. Compared to other affinity membranes for BSA adsorption, the chitosan/sericin membrane exhibited a significantly high adsorption capacity with a comparable adsorption rate.

Original language	English (US)
Pages (from-to)	954-960
Number of pages	7
Journal	Canadian Journal of Chemical Engineering
Volume	95
Issue number	5
DOIs	https://doi.org/10.1002/cjce.22760
State	Published - May 1 2017
Externally published	Yes

Keywords

affinity membrane
bovine serum albumin
chitosan
sericin

ASJC Scopus subject areas

General Chemical Engineering

Online availability

10.1002/cjce.22760

Library availability

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abstract = "Chitosan/sericin blend membranes for adsorption of bovine serum albumin (BSA) were investigated. A preliminary screening test was carried out to identify a suitable chitosan/sericin blend ratio. The blend membrane with a chitosan/sericin mass ratio of 4:1 was found to have a maximum adsorption capacity (qm) of 25.3 g/m2, which is 45 \% greater than the maximum adsorption capacity of the pure chitosan membrane. The adsorption-desorption cycle studies showed that the chitosan/sericin blend affinity membrane could be reused, and over 80 \% of the original adsorption capacity was retained after regeneration. Compared to other affinity membranes for BSA adsorption, the chitosan/sericin membrane exhibited a significantly high adsorption capacity with a comparable adsorption rate.",

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AU - Su, Xiao

AU - Feng, Xianshe

N1 - Research support from the Natural Sciences and Engineering Research Council (NSERC) of Canada is gratefully acknowledged.

PY - 2017/5/1

Y1 - 2017/5/1

N2 - Chitosan/sericin blend membranes for adsorption of bovine serum albumin (BSA) were investigated. A preliminary screening test was carried out to identify a suitable chitosan/sericin blend ratio. The blend membrane with a chitosan/sericin mass ratio of 4:1 was found to have a maximum adsorption capacity (qm) of 25.3 g/m2, which is 45 % greater than the maximum adsorption capacity of the pure chitosan membrane. The adsorption-desorption cycle studies showed that the chitosan/sericin blend affinity membrane could be reused, and over 80 % of the original adsorption capacity was retained after regeneration. Compared to other affinity membranes for BSA adsorption, the chitosan/sericin membrane exhibited a significantly high adsorption capacity with a comparable adsorption rate.

AB - Chitosan/sericin blend membranes for adsorption of bovine serum albumin (BSA) were investigated. A preliminary screening test was carried out to identify a suitable chitosan/sericin blend ratio. The blend membrane with a chitosan/sericin mass ratio of 4:1 was found to have a maximum adsorption capacity (qm) of 25.3 g/m2, which is 45 % greater than the maximum adsorption capacity of the pure chitosan membrane. The adsorption-desorption cycle studies showed that the chitosan/sericin blend affinity membrane could be reused, and over 80 % of the original adsorption capacity was retained after regeneration. Compared to other affinity membranes for BSA adsorption, the chitosan/sericin membrane exhibited a significantly high adsorption capacity with a comparable adsorption rate.

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KW - bovine serum albumin

KW - chitosan

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Chitosan/sericin blend membranes for adsorption of bovine serum albumin

Abstract

Keywords

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