Chapter 17 Bacterial Fatty Acid Synthesis and its Relationships with Polyketide Synthetic Pathways

John E. Cronan, Jacob Thomas

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This review presents the most thoroughly studied bacterial fatty acid synthetic pathway, that of Escherichia coli and then discusses the exceptions to the E. coli pathway present in other bacteria. The known interrelationships between the fatty acid and polyketide synthetic pathways are also assessed, mainly in the Streptomyces group of bacteria. Finally, we present a compendium of methods for analysis of bacterial fatty acid synthetic pathways.

Original languageEnglish (US)
Title of host publicationComplex Enzymes in Microbial Natural Product Biosynthesis, Part B
Subtitle of host publicationPolyketides, Aminocoumarins and Carbohydrates
EditorsDavid Hopwood
Pages395-433
Number of pages39
EditionB
DOIs
StatePublished - Apr 14 2009

Publication series

NameMethods in Enzymology
NumberB
Volume459
ISSN (Print)0076-6879

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ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

Cite this

Cronan, J. E., & Thomas, J. (2009). Chapter 17 Bacterial Fatty Acid Synthesis and its Relationships with Polyketide Synthetic Pathways. In D. Hopwood (Ed.), Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates (B ed., pp. 395-433). (Methods in Enzymology; Vol. 459, No. B). https://doi.org/10.1016/S0076-6879(09)04617-5