Channels of synthesis forty years on: Integrated analysis of spatial economic systems

Isard's vision of integrated modeling that was laid out in the 1960s book Methods of Regional Science provided a road map for the development of more sophisticated analysis of spatial economic systems. Some forty years later, we look back at this vision and trace developments in a sample of three areas - demographic-econometric integrated modeling, spatial interaction modeling, and environmental-economic modeling. Attention will be focused on methodological advances and their motivation by new developments in theory as well as innovations in the applications of these models to address new policy challenges. Underlying the discussion will be an evaluation of the way in which spatial issues have been addressed, ranging from concerns with regionalization to issues of spillovers and spatial correlation.