Channeling to the Nucleus

Hee Jung Chung, Lily Y. Jan

Research output: Contribution to journalShort surveypeer-review

Abstract

L-type voltage-gated calcium channels (LTCs) may control neuronal gene expression by increasing nuclear Ca2+ levels or regulating Ca2+/calmodulin-dependent transcription factors. In the November 3 issue of Cell, Gomez-Ospina et al. demonstrate another signaling mechanism, in which a C-terminal fragment of LTC translocates to the nucleus in a calcium-dependent manner and directly regulates transcription.

Original languageEnglish (US)
Pages (from-to)937-940
Number of pages4
JournalNeuron
Volume52
Issue number6
DOIs
StatePublished - Dec 21 2006
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

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