Abstract
L-type voltage-gated calcium channels (LTCs) may control neuronal gene expression by increasing nuclear Ca2+ levels or regulating Ca2+/calmodulin-dependent transcription factors. In the November 3 issue of Cell, Gomez-Ospina et al. demonstrate another signaling mechanism, in which a C-terminal fragment of LTC translocates to the nucleus in a calcium-dependent manner and directly regulates transcription.
Original language | English (US) |
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Pages (from-to) | 937-940 |
Number of pages | 4 |
Journal | Neuron |
Volume | 52 |
Issue number | 6 |
DOIs | |
State | Published - Dec 21 2006 |
Externally published | Yes |
ASJC Scopus subject areas
- General Neuroscience