Changes in the neuroendocrine control of the female reproductive axis with aging

Phyllis M. Wise, James F. Hyde

Research output: Contribution to journalReview articlepeer-review

Abstract

Major advances in our understanding of the complexities of the perimenopausal process have occurred during the past 5 to 10 years. We now understand that the follicle pool is exhausted at an increasing rate during the last decade of menstrual cyclicity. We are beginning to appreciate that multiple factors, including neuroendocrine changes, may play a role in the perimenopausal period. In addition, it appears that rodents may serve as models for several aspects of menopause.

Original languageEnglish (US)
Pages (from-to)50-54
Number of pages5
JournalCurrent Opinion in Endocrinology and Diabetes
Volume6
Issue number1
DOIs
StatePublished - 1999
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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