Changes in the neuroendocrine control of the female reproductive axis with aging

Phyllis M. Wise, James F. Hyde

    Research output: Contribution to journalReview articlepeer-review

    Abstract

    Major advances in our understanding of the complexities of the perimenopausal process have occurred during the past 5 to 10 years. We now understand that the follicle pool is exhausted at an increasing rate during the last decade of menstrual cyclicity. We are beginning to appreciate that multiple factors, including neuroendocrine changes, may play a role in the perimenopausal period. In addition, it appears that rodents may serve as models for several aspects of menopause.

    Original languageEnglish (US)
    Pages (from-to)50-54
    Number of pages5
    JournalCurrent Opinion in Endocrinology and Diabetes
    Volume6
    Issue number1
    DOIs
    StatePublished - Mar 11 1999

    ASJC Scopus subject areas

    • Internal Medicine
    • Endocrinology, Diabetes and Metabolism
    • Endocrinology

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