Changes in taste perception and eating behavior after bariatric surgery-induced weight loss in women

Marta Yanina Pepino, David Bradley, J. Christopher Eagon, Shelby Sullivan, Nada A. Abumrad, Samuel Klein

Research output: Contribution to journalArticle

Abstract

Objective Roux-en-Y gastric bypass (RYGB) surgery causes greater weight loss than laparoscopic adjustable gastric banding (LAGB). We tested the hypothesis that RYGB has weight loss-independent effects on taste perception, which influence eating behavior and contribute to the greater weight loss. Methods Subjects were studied before and after ∼20% weight loss induced by RYGB (n = 17) or LAGB (n = 10). The following have been evaluated: taste sensitivity for sweet, salty and savory stimuli, sucrose and monosodium glutamate (MSG) preferences, sweetness palatability, eating behavior, and expression of taste-related genes in biopsies of fungiform papillae. Results Weight loss induced by both procedures caused the same decrease in: preferred sucrose concentration (-12 ± 10%), perceived sweetness of sucrose (-7 ± 5%), cravings for sweets and fast-foods (-22 ± 5%), influence of emotions (-27 ± 5%), and external food cues (-30 ± 4%) on eating behavior, and expression of α-gustducin in fungiform papillae (all P values <0.05). RYGB, but not LAGB, shifted sweetness palatability from pleasant to unpleasant when repetitively tasting sucrose (P = 0.05). Neither procedure affected taste detection thresholds nor MSG preferences. Conclusions LAGB and RYGB cause similar alterations in eating behaviors, when weight loss is matched. These changes in eating behavior were not associated with changes in taste sensitivity, suggesting other, as yet unknown, mechanisms are involved.

Original languageEnglish (US)
Pages (from-to)E13-E20
JournalObesity
Volume22
Issue number5
DOIs
StatePublished - May 2014

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Taste Perception
Bariatric Surgery
Feeding Behavior
Gastric Bypass
Weight Loss
Sucrose
Stomach
Sodium Glutamate
Taste Threshold
Satureja
Fast Foods
Cues
Emotions
Biopsy
Food
Genes

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics

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Changes in taste perception and eating behavior after bariatric surgery-induced weight loss in women. / Pepino, Marta Yanina; Bradley, David; Eagon, J. Christopher; Sullivan, Shelby; Abumrad, Nada A.; Klein, Samuel.

In: Obesity, Vol. 22, No. 5, 05.2014, p. E13-E20.

Research output: Contribution to journalArticle

Pepino, MY, Bradley, D, Eagon, JC, Sullivan, S, Abumrad, NA & Klein, S 2014, 'Changes in taste perception and eating behavior after bariatric surgery-induced weight loss in women', Obesity, vol. 22, no. 5, pp. E13-E20. https://doi.org/10.1002/oby.20649
Pepino, Marta Yanina ; Bradley, David ; Eagon, J. Christopher ; Sullivan, Shelby ; Abumrad, Nada A. ; Klein, Samuel. / Changes in taste perception and eating behavior after bariatric surgery-induced weight loss in women. In: Obesity. 2014 ; Vol. 22, No. 5. pp. E13-E20.
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abstract = "Objective Roux-en-Y gastric bypass (RYGB) surgery causes greater weight loss than laparoscopic adjustable gastric banding (LAGB). We tested the hypothesis that RYGB has weight loss-independent effects on taste perception, which influence eating behavior and contribute to the greater weight loss. Methods Subjects were studied before and after ∼20{\%} weight loss induced by RYGB (n = 17) or LAGB (n = 10). The following have been evaluated: taste sensitivity for sweet, salty and savory stimuli, sucrose and monosodium glutamate (MSG) preferences, sweetness palatability, eating behavior, and expression of taste-related genes in biopsies of fungiform papillae. Results Weight loss induced by both procedures caused the same decrease in: preferred sucrose concentration (-12 ± 10{\%}), perceived sweetness of sucrose (-7 ± 5{\%}), cravings for sweets and fast-foods (-22 ± 5{\%}), influence of emotions (-27 ± 5{\%}), and external food cues (-30 ± 4{\%}) on eating behavior, and expression of α-gustducin in fungiform papillae (all P values <0.05). RYGB, but not LAGB, shifted sweetness palatability from pleasant to unpleasant when repetitively tasting sucrose (P = 0.05). Neither procedure affected taste detection thresholds nor MSG preferences. Conclusions LAGB and RYGB cause similar alterations in eating behaviors, when weight loss is matched. These changes in eating behavior were not associated with changes in taste sensitivity, suggesting other, as yet unknown, mechanisms are involved.",
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