TY - JOUR
T1 - Changes in Alcohol Use after Metabolic and Bariatric Surgery
T2 - Predictors and Mechanisms
AU - Ivezaj, Valentina
AU - Benoit, Stephen C.
AU - Davis, Jon
AU - Engel, Scott
AU - Lloret-Linares, Celia
AU - Mitchell, James E.
AU - Pepino, M. Yanina
AU - Rogers, Ann M.
AU - Steffen, Kristine
AU - Sogg, Stephanie
N1 - Publisher Copyright:
© 2019, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2019/9/1
Y1 - 2019/9/1
N2 - Purpose of Review: This review synthesized the literature on predictors and mechanisms of post-bariatric alcohol problems, in order to guide future research on prevention and treatment targets. Recent Findings: Consistent evidence suggests an elevated risk of developing problems with alcohol following bariatric surgery. While there is a paucity of empirical data on predictors of problematic alcohol use after bariatric surgery, being male, a younger age, smoking, regular alcohol consumption, pre-surgical alcohol use disorder, and a lower sense of belonging have predicted alcohol misuse post-operatively. This review synthesizes potential mechanisms including specific bariatric surgical procedures, peptides and reinforcement/reward pathways, pharmacokinetics, and genetic influences. Finally, potential misperceptions regarding mechanisms are explored. Summary: Certain bariatric procedures elevate the risk of alcohol misuse post-operatively. Future research should serve to elucidate the complexities of reward signaling, genetically mediated mechanisms, and pharmacokinetics in relation to alcohol use across gender and developmental period by surgery type.
AB - Purpose of Review: This review synthesized the literature on predictors and mechanisms of post-bariatric alcohol problems, in order to guide future research on prevention and treatment targets. Recent Findings: Consistent evidence suggests an elevated risk of developing problems with alcohol following bariatric surgery. While there is a paucity of empirical data on predictors of problematic alcohol use after bariatric surgery, being male, a younger age, smoking, regular alcohol consumption, pre-surgical alcohol use disorder, and a lower sense of belonging have predicted alcohol misuse post-operatively. This review synthesizes potential mechanisms including specific bariatric surgical procedures, peptides and reinforcement/reward pathways, pharmacokinetics, and genetic influences. Finally, potential misperceptions regarding mechanisms are explored. Summary: Certain bariatric procedures elevate the risk of alcohol misuse post-operatively. Future research should serve to elucidate the complexities of reward signaling, genetically mediated mechanisms, and pharmacokinetics in relation to alcohol use across gender and developmental period by surgery type.
KW - Alcohol
KW - Alcohol use disorder
KW - Bariatric surgery
KW - Obesity
KW - Roux-en-Y gastric bypass
KW - Sleeve gastrectomy
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U2 - 10.1007/s11920-019-1070-8
DO - 10.1007/s11920-019-1070-8
M3 - Review article
C2 - 31410716
AN - SCOPUS:85070707138
SN - 1523-3812
VL - 21
JO - Current Psychiatry Reports
JF - Current Psychiatry Reports
IS - 9
M1 - 85
ER -