Chandelier Cells Illuminate Inhibitory Control of Prefrontal–Amygdala Outputs

Thomas F. Giustino, Stephen Maren

Research output: Contribution to journalShort surveypeer-review

Abstract

Inhibitory interneurons comprise a diverse subpopulation of cells that are critical to circuit function. How distinct inhibitory microcircuits control long-range projections remains poorly understood. A recent study by Lu and colleagues uncovered a unidirectional microcircuit of prefrontal chandelier cells that preferentially innervate and suppress long-range amygdala-projecting pyramidal cells.

Original languageEnglish (US)
Pages (from-to)640-642
Number of pages3
JournalTrends in Neurosciences
Volume40
Issue number11
DOIs
StatePublished - Nov 2017
Externally publishedYes

Keywords

  • amygdala
  • interneurons
  • microcircuits
  • prelimibic

ASJC Scopus subject areas

  • General Neuroscience

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