Central action and a species comparison of the estrogenic effects of an antiestrogen on eating and body weight

Edward J. Roy, Christie A. Maass, George N. Wade

Research output: Contribution to journalArticle

Abstract

The antiestrogen MER-25, which generally inhibits estradiol-induced behavior, is itself fully estrogenic on eating and body weight. In rats, MER-25 decreases food intake when implanted in the same hypothalamic areas in which estradiol decreases food intake. In gerbils, both estradiol benzoate and MER-25 cause increased food intake and body weight.

Original languageEnglish (US)
Pages (from-to)137-140
Number of pages4
JournalPhysiology and Behavior
Volume18
Issue number1
DOIs
StatePublished - Jan 1977

Keywords

  • Antiestrogen
  • Body weight
  • Eating
  • Gerbils
  • Intracerebral hormone implants
  • MER-25

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

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