Central action and a species comparison of the estrogenic effects of an antiestrogen on eating and body weight

Edward J. Roy, Christie A. Maass, George N. Wade

Research output: Contribution to journalArticle

Abstract

The antiestrogen MER-25, which generally inhibits estradiol-induced behavior, is itself fully estrogenic on eating and body weight. In rats, MER-25 decreases food intake when implanted in the same hypothalamic areas in which estradiol decreases food intake. In gerbils, both estradiol benzoate and MER-25 cause increased food intake and body weight.

Original languageEnglish (US)
Pages (from-to)137-140
Number of pages4
JournalPhysiology and Behavior
Volume18
Issue number1
DOIs
StatePublished - Jan 1977

Fingerprint

Ethamoxytriphetol
Estrogen Receptor Modulators
Estrogens
Eating
Body Weight
Estradiol
Gerbillinae

Keywords

  • Antiestrogen
  • Body weight
  • Eating
  • Gerbils
  • Intracerebral hormone implants
  • MER-25

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

Cite this

Central action and a species comparison of the estrogenic effects of an antiestrogen on eating and body weight. / Roy, Edward J.; Maass, Christie A.; Wade, George N.

In: Physiology and Behavior, Vol. 18, No. 1, 01.1977, p. 137-140.

Research output: Contribution to journalArticle

@article{875c5397a12748fb9d3122439d11012c,
title = "Central action and a species comparison of the estrogenic effects of an antiestrogen on eating and body weight",
abstract = "The antiestrogen MER-25, which generally inhibits estradiol-induced behavior, is itself fully estrogenic on eating and body weight. In rats, MER-25 decreases food intake when implanted in the same hypothalamic areas in which estradiol decreases food intake. In gerbils, both estradiol benzoate and MER-25 cause increased food intake and body weight.",
keywords = "Antiestrogen, Body weight, Eating, Gerbils, Intracerebral hormone implants, MER-25",
author = "Roy, {Edward J.} and Maass, {Christie A.} and Wade, {George N.}",
year = "1977",
month = "1",
doi = "10.1016/0031-9384(77)90105-6",
language = "English (US)",
volume = "18",
pages = "137--140",
journal = "Physiology and Behavior",
issn = "0031-9384",
publisher = "Elsevier Inc.",
number = "1",

}

TY - JOUR

T1 - Central action and a species comparison of the estrogenic effects of an antiestrogen on eating and body weight

AU - Roy, Edward J.

AU - Maass, Christie A.

AU - Wade, George N.

PY - 1977/1

Y1 - 1977/1

N2 - The antiestrogen MER-25, which generally inhibits estradiol-induced behavior, is itself fully estrogenic on eating and body weight. In rats, MER-25 decreases food intake when implanted in the same hypothalamic areas in which estradiol decreases food intake. In gerbils, both estradiol benzoate and MER-25 cause increased food intake and body weight.

AB - The antiestrogen MER-25, which generally inhibits estradiol-induced behavior, is itself fully estrogenic on eating and body weight. In rats, MER-25 decreases food intake when implanted in the same hypothalamic areas in which estradiol decreases food intake. In gerbils, both estradiol benzoate and MER-25 cause increased food intake and body weight.

KW - Antiestrogen

KW - Body weight

KW - Eating

KW - Gerbils

KW - Intracerebral hormone implants

KW - MER-25

UR - http://www.scopus.com/inward/record.url?scp=0017597234&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017597234&partnerID=8YFLogxK

U2 - 10.1016/0031-9384(77)90105-6

DO - 10.1016/0031-9384(77)90105-6

M3 - Article

C2 - 905369

AN - SCOPUS:0017597234

VL - 18

SP - 137

EP - 140

JO - Physiology and Behavior

JF - Physiology and Behavior

SN - 0031-9384

IS - 1

ER -