The antiestrogen MER-25, which generally inhibits estradiol-induced behavior, is itself fully estrogenic on eating and body weight. In rats, MER-25 decreases food intake when implanted in the same hypothalamic areas in which estradiol decreases food intake. In gerbils, both estradiol benzoate and MER-25 cause increased food intake and body weight.
- Body weight
- Intracerebral hormone implants
ASJC Scopus subject areas
- Experimental and Cognitive Psychology
- Behavioral Neuroscience