Abstract
The ability of optical coherence tomography (OCT) to image cellular morphology in vivo was evaluated using an animal model. Images were acquired perpendicular to the anteroposterior axis of Xenopus laevis (African frog tadpole). Detailed cellular morphology, including cell membranes and individual cell nuclei, was easily visible using high resolution OCT. Individual cells were also imaged through the cell cycle demonstrating in vivo imaging of cellular processes such as mitosis. OCT imaging in vitro was also performed on a series of human tissues of varying degrees of neoplastic infiltration. The data obtained suggests that OCT-guided diagnosis has the potential to provide early detection of neoplasia and aid the prompt and efficient treatment of cancer.
| Original language | English (US) |
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| Title of host publication | Conference on Lasers and Electro-Optics Europe - Technical Digest |
| Editors | Anon |
| Publisher | IEEE |
| Pages | 127-128 |
| Number of pages | 2 |
| State | Published - 1998 |
| Externally published | Yes |
| Event | Proceedings of the 1998 Conference on Lasers and Electro-Optics, CLEO - San Francisco, CA, USA Duration: May 3 1998 → May 8 1998 |
Other
| Other | Proceedings of the 1998 Conference on Lasers and Electro-Optics, CLEO |
|---|---|
| City | San Francisco, CA, USA |
| Period | 5/3/98 → 5/8/98 |
ASJC Scopus subject areas
- Control and Systems Engineering
- Electrical and Electronic Engineering