Geny i belki deleniia bakterial'nykh kletok.

Translated title of the contribution: Cell division genes and proteins in bacterial cells

A. V. Kukekova, S. N. Borkhenius

Research output: Contribution to journalReview article

Abstract

In this review, genes and proteins involved in cytokinesis and cell proliferation of cell-wall bacteria and mycoplasms are considered. We hope that this comparative analysis of genes and proteins of phylogenetically distant bacteria, including the minimal cells of mycoplasmas, can be useful for understanding the basic principles of prokaryotic cell division. The ftsZ gene was found among representatives of all bacterial groups. The recent data indicate that FtsZ protein plays the central role in the process of bacterial cell division. FtsZ protein was revealed in all Eubacterial groups (including mycoplasmas), in Archaebacteria and chloroplasts, All FtsZ proteins are able to form protofilaments as a result of polymerization in vitro and demonstrate GTF-ase activity. On the base of these properties and some similarities in amino acid sequences with tubulins, it has been suggested that FtsZ protein is an evolutionary ancestor of Eukaryotic tubulins. On the earliest stage of bacterial cytokinesis FtsZ protein assembles into a submembranous Z-ring which encircles bacterial cell in the predivisional site. Some other bacterial proteins take part in stabilization and contraction of the Z-ring, which is considered as a cytoskeleton-like bacterial structure.

Translated title of the contributionCell division genes and proteins in bacterial cells
Original languageRussian
Pages (from-to)519-529
Number of pages11
JournalTsitologiia
Volume42
Issue number6
StatePublished - 2000
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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    Kukekova, A. V., & Borkhenius, S. N. (2000). Geny i belki deleniia bakterial'nykh kletok. Tsitologiia, 42(6), 519-529.