Cell-cell adhesion interface: orthogonal and parallel forces from contraction, protrusion, and retraction

Vivian W. Tang

Research output: Contribution to journal › Review article

Abstract

The epithelial lateral membrane plays a central role in the integration of intercellular signals and, by doing so, is a principal determinant in the emerging properties of epithelial tissues. Mechanical force, when applied to the lateral cell-cell interface, can modulate the strength of adhesion and influence intercellular dynamics. Yet the relationship between mechanical force and epithelial cell behavior is complex and not completely understood. This commentary aims to provide an investigative look at the usage of cellular forces at the epithelial cell-cell adhesion interface.

Original languageEnglish (US)
JournalF1000Research
Volume7
DOIs
StatePublished - Jan 1 2018

Fingerprint

Cell adhesion
Cell Adhesion
Epithelial Cells
Adhesion
Epithelium
Tissue
Membranes

Keywords

  • actin
  • adhesion
  • cell-cell
  • contraction
  • epithelial
  • force
  • intercellular
  • lateral membrane
  • protrusion
  • retraction

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Cell-cell adhesion interface : orthogonal and parallel forces from contraction, protrusion, and retraction. / Tang, Vivian W.

In: F1000Research, Vol. 7, 01.01.2018.

Research output: Contribution to journal › Review article

Tang, VW 2018, 'Cell-cell adhesion interface: orthogonal and parallel forces from contraction, protrusion, and retraction', F1000Research, vol. 7. https://doi.org/10.12688/f1000research.15860.1
Tang VW. Cell-cell adhesion interface: orthogonal and parallel forces from contraction, protrusion, and retraction. F1000Research. 2018 Jan 1;7. https://doi.org/10.12688/f1000research.15860.1
Tang, Vivian W. / Cell-cell adhesion interface : orthogonal and parallel forces from contraction, protrusion, and retraction. In: F1000Research. 2018 ; Vol. 7.
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