Abstract

Joint disease is a major cause of wastage in performance horses. Arthritis can be challenging to treat because articular cartilage has little or no capacity for repair, therapeutic options are limited and are largely targeted at ameliorating clinical signs of joint disease. Cell-based therapies have potential to overcome the intrinsic constraints to articular cartilage repair. This article focuses on cell-based therapies for treatment of equine joint disease. Results from experimental model and human clinical studies are presented along with available data from equine studies.

Original languageEnglish (US)
Pages (from-to)335-349
Number of pages15
JournalVeterinary Clinics of North America - Equine Practice
Volume27
Issue number2
DOIs
StatePublished - Aug 1 2011

Fingerprint

Horse Diseases
joint diseases
Joint Diseases
Cell- and Tissue-Based Therapy
Articular Cartilage
horses
cartilage
therapeutics
Horses
arthritis
cells
Arthritis
clinical trials
Theoretical Models
Therapeutics

Keywords

  • Cartilage
  • Cell-based therapy
  • Intra-articular disease
  • Osteoarthritis
  • Resurfacing
  • Soft tissue injury

ASJC Scopus subject areas

  • Equine

Cite this

Cell-based Therapies for Equine Joint Disease. / Frisbie, David D.; Stewart, Matthew C.

In: Veterinary Clinics of North America - Equine Practice, Vol. 27, No. 2, 01.08.2011, p. 335-349.

Research output: Contribution to journalReview article

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