Abstract

This article focuses on current issues facing cell-based therapies in equine practice and future studies validating the use of stem cells and related biologic therapies for the treatment of musculoskeletal conditions in the horse. Issues raised include the characterization and use of tissue- and anatomic location-specific mesenchymal stem cell (MSC) sources, the putative advantages and feasibility of allogeneic embryonic stem cell and MSC products, the technical advantages and performance of cell-based biologic agents that do not require extensive ex vivo manipulation, the regulation of MSC homing, potential nonorthopaedic stem cell applications, and the logistics required to demonstrate cell-based therapy efficacy in horses.

Original languageEnglish (US)
Pages (from-to)393-399
Number of pages7
JournalVeterinary Clinics of North America - Equine Practice
Volume27
Issue number2
DOIs
StatePublished - Aug 1 2011

Fingerprint

Cell- and Tissue-Based Therapy
Mesenchymal Stromal Cells
Horses
stem cells
therapeutics
Stem Cells
Biological Therapy
horses
Biological Factors
cells
Embryonic Stem Cells
embryonic stem cells
Direction compound
Therapeutics

Keywords

  • Biologics
  • Clinical trials
  • Efficacy
  • Mesenchymal stem cells

ASJC Scopus subject areas

  • Equine

Cite this

Cell-based Therapies : Current Issues and Future Directions. / Stewart, Matthew C.

In: Veterinary Clinics of North America - Equine Practice, Vol. 27, No. 2, 01.08.2011, p. 393-399.

Research output: Contribution to journalReview article

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