Catalytic Enantioselective Aldol Additions with Chiral Lewis Bases

Scott E. Denmark, Shinji Fujimori

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter contains sections titled: Introduction Preparation of Enoxytrichlorosilanes Preparation of Chiral Lewis Bases Enantioselective Aldol Addition of Achiral Enoxytrichlorosilanes Diastereoselective Additions of Chiral Enoxytrichlorosilanes Aldol Additions of Aldehyde-derived Enoxytrichlorosilanes Aldol Addition of Trichlorosilyl Ketene Acetal to Aldehydes and Ketones Lewis Base Activation of Lewis Acids -Aldol Additions of Silyl Enol Ethers to Aldehydes Toward a United Mechanistic Scheme Conclusions and Outlook Representative Procedures.

Original languageEnglish (US)
Title of host publicationModern Aldol Reactions
Subtitle of host publicationVol. 1: Enolates, Organocatalysis, Biocatalysis and Natural Product Synthesis
PublisherWiley
Pages229-326
Number of pages98
Volume1
ISBN (Electronic)9783527619566
ISBN (Print)9783527307142
DOIs
StatePublished - Jan 1 2008

Keywords

  • aldol addition reaction
  • formulation
  • geometry
  • organization
  • transmetalation

ASJC Scopus subject areas

  • General Chemistry

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