Abstract
Nodaviruses are small bisegmented RNA viruses belonging to the family Nodaviridae. Nodaviruses have been identified in different hosts, including insects, fishes, shrimps, prawns, dogs, and bats. A novel porcine nodavirus was first identified in the United States by applying next-generation sequencing on brain tissues of pigs with neurological signs, including uncontrollable shaking. RNA1 of the porcine nodavirus had the highest nucleotide identity (51.1%) to the Flock House virus, whereas its RNA2 shared the highest nucleotide identity (48%) with the RNA2 segment of caninovirus (Canine nodavirus). Genetic characterization classified porcine nodavirus as a new species under the genus Alphanodavirus. Further studies are needed to understand the pathogenicity and clinical impacts of this virus.
Original language | English (US) |
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Article number | 73 |
Journal | Viruses |
Volume | 13 |
Issue number | 1 |
DOIs | |
State | Published - Jan 7 2021 |
Keywords
- porcine nodavirus
- United States
- characterization
- detection
- genome
ASJC Scopus subject areas
- Infectious Diseases
- Virology