Cardiovascular fitness and neurocognitive function in older Adults: A brief review

Edward McAuley, Arthur F. Kramer, Stanley J. Colcombe

Research output: Contribution to journalShort surveypeer-review


We provide a brief review of the extant research on the influence of cardiovascular fitness training on brain and cognition. The review includes an examination of the non-human animal literature that has reported molecular, cellular, and behavioral consequences of fitness interventions. We relate this literature to human studies of the relationship between fitness and cognition, as well as the nascent literature on fitness influences on human brain structure and function with state-of-the art neuroimaging techniques. We also consider the important topic of participant adherence in clinical exercise trials. Finally, we suggest future directions for studies of cardiovascular fitness, aging, and neurocognitive function.

Original languageEnglish (US)
Pages (from-to)214-220
Number of pages7
JournalBrain, Behavior, and Immunity
Issue number3
StatePublished - May 2004


  • Adherence
  • Aging
  • Behavioral interventions
  • Brain function
  • Brain structure
  • Cardiovascular fitness
  • Cognitive function

ASJC Scopus subject areas

  • Immunology
  • Endocrine and Autonomic Systems
  • Behavioral Neuroscience


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