Carcinoma in situ within an area of Barrett esophagus in a dog with megaesophagus

Matthew A. Kopke, John S. Munday, Arnon Gal

Research output: Contribution to journalArticlepeer-review


A 10-y-old Irish Setter was presented with a history of recurrent episodes of regurgitation and vomiting, with more recent development of tachypnea. Megaesophagus had been diagnosed in the dog 2 y prior to this presentation. A solitary polypoid mass present immediately rostral to the lower esophageal sphincter was biopsied during percutaneous endoscopic gastrostomy tube placement. Barrett esophagus was diagnosed based on the observation of a polypoid mass with intestinal metaplasia that arose from the surrounding esophagus. Histology of the polypoid mass demonstrated squamous-to-columnar metaplasia, hyperplasia, dysplasia, and carcinoma in situ.

Original languageEnglish (US)
Pages (from-to)752-754
Number of pages3
JournalJournal of Veterinary Diagnostic Investigation
Issue number5
StatePublished - Sep 1 2018
Externally publishedYes


  • Canine
  • esophagitis
  • gastroesophageal reflux disease
  • intestinal metaplasia
  • regurgitation

ASJC Scopus subject areas

  • veterinary(all)


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