Can normal mode analysis reveal the geometry of the L550 chromophore of bacteriorhodopsin?

M. F. Großjean, P. Tavan, K. Schulten

Research output: Contribution to journalArticlepeer-review


We discuss to what extent recent vibrational spectra of 14-2H, 15-2H and 14,15-2H isotopically labelled L550 provide evidence for the occurrence of 13-cis, 14-s-trans or 13-cis, 14-s-cis chromophore structures in bacteriorhodopsin's photocycle. The discussion is based on a quantum chemical (MNDO) vibrational analysis of four molecular fragments as models for the retinal chromophore in bacteriorhodopsin.

Original languageEnglish (US)
Pages (from-to)341-349
Number of pages9
JournalEuropean Biophysics Journal
Issue number6
StatePublished - Feb 1 1989


  • Bacteriorhodopsin
  • retinal
  • vibrational analysis

ASJC Scopus subject areas

  • Biophysics


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